The short answer is: no.
From gnu.org:
** Emacs can now be compiled with file notification support. This happens by default if a suitable system library is found at build time. To prevent this, use the configure option `--without-file-notification'. See below for file-notify features. This feature is not available for the Nextstep port.
EDIT:
From the quote above, we can say Note that Notification on file changes is not supported on Nextstep OS"Nextstep", in this context, means "OS X". There's a lengthy explanation of this confusing terminology here.
From Wikipedia:
[...] Apple's OS X and iOS are direct descendants of NeXTSTEP, through the OPENSTEP lineage.
Quote 1 + quote 2 = Notification on file changes is not supported on Mac OSX.