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My intention is to represent the molecular docking in a very schematic way. What you see here is the protein, and the cavity represents its active site. To represent the ligand molecule I would need to draw, in a separate image, the complementary part of the circle. Maybe, also a method to obtain the same image without having to rotate it. Any ideas?

\documentclass{standalone} \usepackage{tikz} \begin{document} \begin{tikzpicture} \filldraw[fill opacity=0.5,fill=blue,rotate=23] (0,0) -- (4,0) arc (0:315:4.0cm) -- cycle; \end{tikzpicture} \end{document} 

enter image description here

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    Are you looking for \begin{tikzpicture} \filldraw[fill opacity=0.5,fill=orange,rotate=-23] (0,0) -- (4,0) arc (0:360-315:4.0cm) -- cycle; \end{tikzpicture}? Commented Nov 11, 2024 at 16:52

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\documentclass[tikz, border=1cm]{standalone} \begin{document} \begin{tikzpicture} \fill[blue!50] (0,0) -- (23:4) arc[start angle=23, end angle=360-23, radius=4] -- cycle; \fill[blue!50, xshift=10cm] (0,0) -- (23:4) arc[start angle=23, end angle=-23, radius=4] -- cycle; \fill[blue!50, yshift=-10cm] (-4,-4) rectangle (4,4) (0,0) -- (23:4) arc[start angle=23, end angle=360-23, radius=4] -- cycle; \fill[blue!50, xshift=10cm, yshift=-10cm, even odd rule] (0,0) -- (23:4) arc[start angle=23, end angle=360-23, radius=4] -- cycle (1.2,2.5) circle[radius=0.8]; \fill[xshift=10cm, yshift=-10cm] (1,2.4) circle[radius=0.4]; \end{tikzpicture} \end{document} 

Four shapes of circle cuts

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    The bottom right one is the best! Commented Nov 11, 2024 at 17:14

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