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Nov 30, 2020 at 17:21 answer added chrishmorris timeline score: 0
Nov 28, 2020 at 15:29 history edited M__
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Feb 16, 2020 at 20:10 history edited M__
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Feb 16, 2020 at 17:02 answer added M__ timeline score: 2
Feb 14, 2020 at 21:26 comment added Devon Ryan Sure, transgenes will make things obvious, but they're not generally present when we genetically modify something.
Feb 14, 2020 at 21:22 comment added yters @DevonRyan can we at least guarantee true positives with high reliability? It seems to be the case, e.g. if we see a massive segment of DNA from a totally different species spliced into the DNA sequence we are examining. I'm asking if there is a good general methodology for at least identifying true positives reliably, even if we cannot identify true negatives reliably.
Feb 14, 2020 at 20:10 comment added Devon Ryan For the record, there is no guaranteed way to do this, it'd be completely impossible. We genetically engineer things all the time by just changing a few bases to things that already naturally occur in the species (but not at the same time in the wild) to speed up animal/crop breeding, as a simple example.
Feb 14, 2020 at 20:03 comment added yters @MichaelG. since you reference conspiracy theories, probably in regard to the coronavirus outbreak: for the record, I do not think the Wuhan coronavirus is genetically engineered. But, the conspiracy theories made me wonder if there is a reliable way to detect whether genetically engineering has occurred in genetic data.
Feb 14, 2020 at 19:46 comment added Mack123456 Researcher have generated transgenic organisms for over a century. So yes there are many "modified genomes" available. You could also take any strain of interest, modify a few nucleotides, add some indels, or even an entire gene and analyze that. For step 3 for example, you could take humanized mouse or fly models used in disease biology...
Feb 14, 2020 at 16:50 review Close votes
Feb 16, 2020 at 20:54
Feb 14, 2020 at 16:26 history edited yters CC BY-SA 4.0
Note on research I've done.
Feb 14, 2020 at 16:11 history asked yters CC BY-SA 4.0