Python 2.7, 133 bytes
def e(a, b): c, d = """2,too,to,t0,two""","""be,b,bee,b3""" return a.lower() in c and b.lower() in d print e('2', 'bee') Not sure if we're supposed to post solutions if there's a smaller version in the comments but here's my version in Python.
Edit: Without the function it's only 73 bytes (and that's not even near the best answers. Forgive me I'm new
a, b = "to", "bee" print a in "2 too to t0 two" and b in "be b bee b3"