I have an experimental PSF (point spread function) of an optical system for remote sensing images. However, it is asymmetrical and has some sidelobes as below.
And I want to perform deconvolution to sharpen the images.
Is it possible to use this PSF as it is to sharpen the images? Or should there be some modifications and enhancements for the PSF before using it? Also, is there an available reference paper tackling such an issue?

some modifications and enhancements for the PSF before using itwere developed, too. Try web search with keywords 'remote sensing images, richardson lucy algorithm'. You can hardly expect quality answers with unspecific questions like those of your post. Or is your question just recon? $\endgroup$