Try adding quick-slots for the most used powers like in Diablo 2, Torchlight ,Titan Quest, World of Warcraft etc..

Let the player assign whatever skills he wants to these hotkeys without having to go into your options menu.

This adds to the excitement for the user, since he can try to create as effective hotkey combos as possible.

Try adding quick-slots for the most used powers like in Diablo 2, Torchlight ,Titan Quest, World of Warcraft etc..

Let the player assign whatever skills he wants to these hotkeys without having to go into your options menu.

This adds to the excitement for the user, since he can try to create as effective hotkey combos as possible.

EDIT:

If it wasn't clear I meant for you to keep the number key mapping like you already have, but add the possibility to map which skill is where.

You could also have be able to map Q and E to your bindings.

Conan did this quite well with their combo combat. In conan you could hit 1,2,3,Q and E for directional attacks. These buttons are close enough for the player to hit them.