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BUG / API: setitem on pandas object fails if underlying numpy array is read-only

API Design

IndexingRelated to indexing on series/frames, not to indexes themselvesRelated to indexing on series/frames, not to indexes themselves

Status: Open.

#62144 In pandas-dev/pandas;

· jorisvandenbossche opened on Aug 19, 2025

· 

3.1

BUG: Setting multiple values via .loc produces NaNs with MultiIndex

Bug

IndexingRelated to indexing on series/frames, not to indexes themselvesRelated to indexing on series/frames, not to indexes themselves

MultiIndex

RegressionFunctionality that used to work in a prior pandas versionFunctionality that used to work in a prior pandas version

Status: Open.

#46837 In pandas-dev/pandas;

· LustigerKernSpalt opened on Apr 22, 2022

BUG: <code>DataFrame.loc</code> is not consistent with <code>DataFrame.__setitem__</code> when used with 2D numpy array

Bug

IndexingRelated to indexing on series/frames, not to indexes themselvesRelated to indexing on series/frames, not to indexes themselves

RegressionFunctionality that used to work in a prior pandas versionFunctionality that used to work in a prior pandas version

Status: Open.

#46544 In pandas-dev/pandas;

· anmyachev opened on Mar 28, 2022

BUG: Selecting multiple columns from data frames with MultiIndex columns raises "ValueError" when each level of index is tuple

Bug

IndexingRelated to indexing on series/frames, not to indexes themselvesRelated to indexing on series/frames, not to indexes themselves

MultiIndex

Nested DataData where the values are collections (lists, sets, dicts, objects, etc.).Data where the values are collections (lists, sets, dicts, objects, etc.).

Status: Open.

#43780 In pandas-dev/pandas;

· tiezhishizi opened on Sep 28, 2021

BUG: Assigning extension array value to series of dtype object fails if element type is array-like

Bug

ExtensionArrayExtending pandas with custom dtypes or arrays.Extending pandas with custom dtypes or arrays.

good first issue

IndexingRelated to indexing on series/frames, not to indexes themselvesRelated to indexing on series/frames, not to indexes themselves

Needs TestsUnit test(s) needed to prevent regressionsUnit test(s) needed to prevent regressions

RegressionFunctionality that used to work in a prior pandas versionFunctionality that used to work in a prior pandas version

Status: Open.

#42437 In pandas-dev/pandas;

· frreiss opened on Jul 7, 2021

API: require scalar result from the scalar .at indexer

API Design

IndexingRelated to indexing on series/frames, not to indexes themselvesRelated to indexing on series/frames, not to indexes themselves

Needs DiscussionRequires discussion from core team before further actionRequires discussion from core team before further action

Status: Open.

#33153 In pandas-dev/pandas;

· jorisvandenbossche opened on Mar 30, 2020

get start and end of regex match in dataframe

Enhancement

IndexingRelated to indexing on series/frames, not to indexes themselvesRelated to indexing on series/frames, not to indexes themselves

StringsString extension data type and string dataString extension data type and string data

Status: Open.

#8747 In pandas-dev/pandas;

· teese opened on Nov 6, 2014