When you try to solve a degree n$n$ equation, there are n$n$ roots you have to find (in principle) and none of them is favoured over any of the others, which (in some metaphorical sense) means that you have to break an n$n$-fold symmetry in order to write down the roots.
Now the symmetry group of the n roots becomes more and more complicated the larger n$n$ is. For n = 2$n = 2$, it is abelian (and very small!); for n = 3$n = 3$ and 4$4$ it is still solvable (in the technical sense of group theory), which explains the existence of an explicit formula involving radicals (this is due to Galois, and is a part of so-called Galois theory); for n = 5$n = 5$ or more this group is non-solvable (in the technical sense of group theory), and this corresponds to the fact that there is no explicit formula involving radicals.
Summary: The complexity of the symmetry group of the n$n$ roots leads to a corresponding complexity in explicitly solving the equation.