EDIT: Well, this was impressively wrong: not only did I somehow spend most of the answer thinking "ordered space" meant "linearly ordered space," I also missed the significance of the OP's restriction to universal Horn structures. Below is a heavily edited version of my original post. As it stands, this is not an answer, just a too-long comment. (My apologies to the OP.)
First, Wikipedia has the definition of ordered space: http://en.wikipedia.org/wiki/Partially_ordered_spacehttps://en.wikipedia.org/wiki/Partially_ordered_space.
As to first-order structures which are "compatible" with a given topology, let me say three things:
When studying topological structures, we don't always care about any sort of compatibility. See See Ziegler's article "Topological model theory" (http://projecteuclid.org/DPubS/Repository/1.0/Disseminate?handle=euclid.pl/1235417281&view=body&content-type=pdf_1https://projecteuclid.org/euclid.pl/1235417281) in Model-Theoretic Logics. Obviously, this isn't what you're talking about, but I think it's worth mentioning - especially if you start looking around for topological model theory, just so one is aware that frequently no such compatibility is required.
If the complexity of the structure is not restricted, then we don't always want relations to be closed; sometimes we want relations to be open. This is the approach taken by Robinson (http://matwbn.icm.edu.pl/ksiazki/fm/fm81/fm81115.pdf). On the other hand, we could simply demand that every predicate be closed; the price of that would be that some reasonable topologies on some natural first-order structures would be ommitted.
I don't know of a structure $M$ with a natural topology $\tau$ where $M$ is universal Horn and $\tau$ does not make all predicates closed; however, this doesn't mean that such structures aren't interesting. As an example, given a universal Horn structure $\mathcal{M}$ with a topology $\tau$, it is reasonable to consider adjoining a predicate $U$ to $\mathcal{M}$ naming a specific open subset of $\mathcal{M}$. The resulting expansion $\mathcal{M}^+$ might still be universal Horn, but now it's not clear to me that it's natural to want $U^{\mathcal{M}^+}$ to now be clopen. I think even in the universal Horn cases, demanding all predicates be closed might kill off some neat objects.