If the oldvalueold value is nullthenull the result of the equations should rightly be null. This is becasuebecause null is not a number, it means unknown value. Therefore the calcaluationcalculation cannot proceed.
Of course your equation also fails if oldvalue = 0old value = 0 as you cannot divide by zero.
Typically you handle these things with a case statmentstatement that will take you the path of what you want to show. So if you want the result to show as null when you can't calculate (as with a null or a zero, then you would do a case statmentstatement something like
case when [oldvalue][old value] = 0 then null else 100 * (([old value] - [new value]) /[old value]) end