Hum Genet
 2016
DOI: 10.1007/s00439-016-1742-y
|Get access via publisher |Summarize |Cite|
|
Sign up to set email alerts

Complete mitochondrial genomes of Thai and Lao populations indicate an ancient origin of Austroasiatic groups and demic diffusion in the spread of Tai–Kadai languages

Wibhu Kutanan
1
,
Jatupol Kampuansai
2
,
Metawee Srikummool
3
et al.

Abstract: The Tai–Kadai (TK) language family is thought to have originated in southern China and spread to Thailand and Laos, but it is not clear if TK languages spread by demic diffusion (i.e., a migration of people from southern China) or by cultural diffusion, with native Austroasiatic (AA) speakers switching to TK languages. To address this and other questions, we obtained 1234 complete mtDNA genome sequences from 51 TK and AA groups from Thailand and Laos. We find high genetic heterogeneity across the region, with … Show more

Help me understand this report
View preprint versions

Search citation statements

Order By: Relevance

Paper Sections

Select...
95
23
19
14

Citation Types

20
121
2
5

Year Published

2017
2017
2026
2026

Publication Types

Select...
74
38
16

Relationship

17
111

Authors

Journals

citations

Cited by 126 publications

(148 citation statements)
references

References 63 publications

20
121
2
5
Order By: Relevance
“…The STRUCTRUE results indicated that K = 6 is the most appropriate △ K for describing sub-structuring of populations ( Supplementary Figure S2 ) and at K = 6 all populations shared a common blue component with different proportions. In general, the AA speaking groups have reduced blue component but show additional various minor components, indicating their genetic differentiation from each other and from the TK speaking groups, which is consistent with previous mtDNA, Y chromosome and genome-wide studies ( Kutanan et al, 2014 ; Kutanan et al, 2017 ; Kutanan et al, 2019 ; Kutanan et al, 2021 ). Genetic drift, isolation and population interactions with other groups are factors promoting genetic differentiations of AA speaking groups in Thailand ( Kutanan et al, 2018 ; Kutanan et al, 2021 ).…”
Section: Resultssupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…The STRUCTRUE results indicated that K = 6 is the most appropriate △ K for describing sub-structuring of populations ( Supplementary Figure S2 ) and at K = 6 all populations shared a common blue component with different proportions. In general, the AA speaking groups have reduced blue component but show additional various minor components, indicating their genetic differentiation from each other and from the TK speaking groups, which is consistent with previous mtDNA, Y chromosome and genome-wide studies ( Kutanan et al, 2014 ; Kutanan et al, 2017 ; Kutanan et al, 2019 ; Kutanan et al, 2021 ). Genetic drift, isolation and population interactions with other groups are factors promoting genetic differentiations of AA speaking groups in Thailand ( Kutanan et al, 2018 ; Kutanan et al, 2021 ).…”
Section: Resultssupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…We analyzed haplogroups that have additional sequences from the present study and have more than five sequences in total (Table 3 ). The ages of major haplogroups are generally consistent with previous studies [ 7 ]. However, we obtained more data from several sublineages which were not dated previously, e.g., B4c1b, B6a1, C4, C7a, D4a, F1c, F1e, F1g, F2, F3, F4a2, and G2a (Table 3 ).…”
Section: Resultssupporting
confidence: 90%
“…The present study adds to our previous study of Thai/Lao mtDNA genome sequences by including 22 additional groups from Thailand, including the AA-speaking Mon (MO), ST-speaking Karen, and several TK speaking groups, especially the CT. Similar to our previous mtDNA study [ 7 ], genetic heterogeneity among populations belonging to the same ethnic groups was still observed, especially for the Karen (the hill tribes) (Figs. 1 , 4 and 5 ).…”
Section: Discussionsupporting
confidence: 89%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…In agreement with earlier studies of mtDNA and autosomal STRs variation [ 20 – 22 ] that reported genetic differentiation of MK speaking groups in northern Thailand, the two LW groups appeared to differ from other populations and from each other, as indicated by the DAPC results ( S2C Fig ). A lower level of gene flow caused by the presence of geographic barriers may be the driven factor of this differentiation, as suggested by the EEMS surfaces ( Fig 4 ).…”
Section: Discussionsupporting
confidence: 92%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
scite logo

Scite is an AI-powered platform that helps researchers discover and evaluate scientific literature through Smart Citations, showing whether studies support or contradict a claim. Now part of Research Solutions, Scite has indexed 1.6B+ citations, partners with 30+ publishers, and serves 2M users worldwide.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Status

Copyright © 2026 Scite LLC. All rights reserved.

Made with 💙 for researchers

Part of the Research Solutions Family.

Research Solutions Logo