Using [Miller](https://github.com/johnkerl/miller):

 mlr --tsv --implicit-csv-header --headerless-csv-output \
 put -S '$1=gsub($1,"[+].+$","")' inputfile

and the output is:

 ICR1 +
 ICR1 +
 ICR1 +
 IRT1 +
 IRT1 +
 IRT1 +
 LSR1 -
 LSR1 -
 LSR1 -
 NME1 +
 NME1 +
 NME1 +
 PWR1 -
 PWR1 -
 PWR1 -
 Q0017 -
 Q0017 -
 Q0020 -
 Q0020 -
 Q0020 -