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Using the search box at the top of GitHub pages, you can perform a variety of searches.

To view issues you've commented on use the following search string:
_{Sample Search URL}

is:issue commenter:@me 

To show only open issues, add the is:open qualifier:
_{Sample Search URL}

is:issue commenter:@me is:open 

The search can also be adapted for any user by replacing @me with their GitHub username. Do not include the @ symbol in this case.

For example, for the username defunkt/@defunkt use:
_{Sample Search URL}

is:issue commenter:defunkt 

Source: GitHub Docs, Searching issues and pull requests