 | | DRUG: Oxycodone hydrochloride | |
| Entry | |
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| Name | Oxycodone hydrochloride (USP);
Oxecta (TN);
Oxycontin (TN);
Roxicodone (TN) |
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| Product | |
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| Generic | OXYCODONE HCL (Amneal Pharmaceuticals NY LLC), OXYCODONE HCL (Direct_Rx), OXYCODONE HCL (Direct_Rx), OXYCODONE HCL (Direct_Rx), OXYCODONE HCL (Direct_Rx), OXYCODONE HCL (Direct_Rx), OXYCODONE HYDCHLORIDE (Quality Care Products LLC), OXYCODONE HYDCHLORIDE (Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (ANI Pharmaceuticals), OXYCODONE HYDROCHLORIDE (ANI Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Alvogen), OXYCODONE HYDROCHLORIDE (American Health Packaging), OXYCODONE HYDROCHLORIDE (American Health Packaging), OXYCODONE HYDROCHLORIDE (Amneal Pharmaceuticals LLC), OXYCODONE HYDROCHLORIDE (Ascent Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Asclemed USA), OXYCODONE HYDROCHLORIDE (Asclemed USA), OXYCODONE HYDROCHLORIDE (Asclemed USA), OXYCODONE HYDROCHLORIDE (Aurolife Pharma), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Camber Pharmaceuticals), OXYCODONE HYDROCHLORIDE (DIRECT RX), OXYCODONE HYDROCHLORIDE (Epic Pharma), OXYCODONE HYDROCHLORIDE (Eywa Pharma), OXYCODONE HYDROCHLORIDE (Eywa Pharma), OXYCODONE HYDROCHLORIDE (Hikma Pharmceuticals USA), OXYCODONE HYDROCHLORIDE (KVK-TECH), OXYCODONE HYDROCHLORIDE (KVK-TECH), OXYCODONE HYDROCHLORIDE (KVK-Tech), OXYCODONE HYDROCHLORIDE (Lupin Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Lupin Pharmaceuticals), OXYCODONE HYDROCHLORIDE (MAJOR PHARMACEUTICALS), OXYCODONE HYDROCHLORIDE (MAJOR PHARMACEUTICALS), OXYCODONE HYDROCHLORIDE (Major Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Novel Laboratories), OXYCODONE HYDROCHLORIDE (NuCare Pharmaceuticals), OXYCODONE HYDROCHLORIDE (NuCare Pharmaceuticals), OXYCODONE HYDROCHLORIDE (NuCare Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PAI Holdings), OXYCODONE HYDROCHLORIDE (Precision Dose), OXYCODONE HYDROCHLORIDE (QUAGEN PHARMACEUTICALS LLC), OXYCODONE HYDROCHLORIDE (Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (RedPharm Drug), OXYCODONE HYDROCHLORIDE (Redpharm Drug), OXYCODONE HYDROCHLORIDE (Rhodes Pharmaceuticals L.P.), OXYCODONE HYDROCHLORIDE (ST. MARY'S MEDICAL PARK PHARMACY), OXYCODONE HYDROCHLORIDE (ST. MARY'S MEDICAL PARK PHARMACY), OXYCODONE HYDROCHLORIDE (ST. MARY'S MEDICAL PARK PHARMACY), OXYCODONE HYDROCHLORIDE (ST. MARY'S MEDICAL PARK PHARMACY), OXYCODONE HYDROCHLORIDE (SpecGx LLC), OXYCODONE HYDROCHLORIDE (SpecGx LLC), OXYCODONE HYDROCHLORIDE (Strides Pharma Science Limited), OXYCODONE HYDROCHLORIDE (XLCare Pharmaceuticals), OXYCODONE HYDROCHLORIDE ORAL SOLUTION (Aurolife Pharma) |
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| Formula | C18H21NO4. HCl
|
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| Exact mass | 351.1237
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| Mol weight | 351.82
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| Structure | 
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| Simcomp | |
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| Class | Neuropsychiatric agent
DG01564 Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
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| Remark | | Product (DG00813): | D05312<US> D00847<US> D05462<JP> |
| Product (mixture): | D02153<US> D11176<US> |
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| Efficacy | Analgesic (narcotic), Opioid receptor agonist |
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| Comment | Opium alkaloid
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| Target | |
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| Pathway | | hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Metabolism | Enzyme: CYP3A4 [HSA: 1576]; CYP2D6 [HSA: 1565] |
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| Interaction | |
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| Structure map | | map07224 | Opioid receptor agonists/antagonists |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AA Natural opium alkaloids
N02AA05 Oxycodone
D00847 Oxycodone hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Analgesics
Opioid Analgesics, Long-acting
Oxycodone
D00847 Oxycodone hydrochloride (USP)
Opioid Analgesics, Short-acting
Oxycodone
D00847 Oxycodone hydrochloride (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00813 Oxycodone
D00847 Oxycodone hydrochloride
Analgesic
DG01984 Opioid analgesics
DG00813 Oxycodone
D00847 Oxycodone hydrochloride
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00813 Oxycodone
D00847 Oxycodone hydrochloride
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00813 Oxycodone
D00847 Oxycodone hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D00847 Oxycodone hydrochloride (USP) <US>
OPRK1
D00847 Oxycodone hydrochloride (USP) <US>
OPRD1
D00847 Oxycodone hydrochloride (USP) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00847
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00813 Oxycodone
Analgesic
DG01984 Opioid analgesics
DG00813 Oxycodone
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00813 Oxycodone
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00813 Oxycodone
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| Other DBs | |
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| LinkDB | |
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| KCF data |
ATOM 24
1 C1z C 24.4381 -17.6672
2 C8y C 24.4321 -16.3168
3 C1z C 25.6030 -18.3338
4 C1y C 23.2847 -18.3454
5 C8y C 23.2672 -15.6445
6 C8y C 25.5972 -15.6445
7 C1y C 26.7623 -17.6499
8 C1x C 25.6087 -19.6668
9 O1a O 26.7623 -19.2729
10 O2x O 22.5833 -17.0126
11 C5x C 23.2905 -19.6784
12 C8y C 23.2672 -14.2999
13 C1x C 26.7623 -16.3109
14 C8x C 25.5972 -14.2999
15 N1y N 27.9213 -18.3221
16 C1x C 24.4554 -20.3450
17 O5x O 22.1139 -20.3391
18 C8x C 24.4321 -13.6277
19 O2a O 22.0966 -13.6277
20 C1a C 29.2659 -18.3221
21 C1x C 27.9213 -16.9998
22 C1x C 25.6435 -17.0412
23 C1a C 20.8657 -14.3423
24 X Cl 29.6100 -14.9100
BOND 27
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 2
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1 #Down
10 4 11 1
11 5 12 2
12 6 13 1
13 6 14 1
14 7 15 1 #Up
15 8 16 1
16 11 17 2
17 12 18 1
18 12 19 1
19 15 20 1
20 5 10 1
21 7 13 1
22 11 16 1
23 14 18 2
24 15 21 1
25 1 22 1 #Up
26 22 21 1
27 19 23 1
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