debilitating

I forgit myself when I take such an interest in your breakfast, as to wish your frame, exhausted by the debilitating effects of prodigygality, to be stimilated by the 'olesome nourishment of your forefathers.

"Jes' lemme think a bit," said Bert, finding the stare debilitating. "Look 'ere I" he said at last, with an air of great explicitness, "I GOT the secret."

In his latest book, The End of Polio, he traveled to five countries, Congo, India, Pakistan, Somalia and Sudan, to chronicle the lives of the people living there, struggling to rid their lives of a preventable yet debilitating disease--all efforts of World Health Organization's (WHO) Polio Eradication Initiative.

Twenty percent of Crohn's patients have debilitating perianal fistulas, and the quality of life of these patients is severely reduced.

Unwavering in her critique of the economic and social forces that define gender and sexuality, Feinberg reiterates much that she's already said (all forms of oppression are linked; unity is empowering, divisiveness debilitating).

The nation has suffered a number of debilitating recessions in recent decades.

People who exhibit prolonged, debilitating grief after a loved one's death often improve markedly upon receiving a novel type of psychotherapy that focuses on finding ways to adjust to the loss, says a team led by psychiatrist Katherine Shear of the University of Pittsburgh School of Medicine.

The company has pioneered new treatments for some of the world's most debilitating conditions including asthma, Parkinson's disease, drug addiction, erectile dysfunction and surgical adhesions.

You Know Better is poignant for its searing views on the debilitating state of black families, teens that have grown up on a diet of misogynist and violent imagery, and the rampant materialism of today's society.

This debilitating condition, called pulmonary hypertension, constricts lung arteries.

The CPMP's recommendation on Kineret(R) clearly demonstrates that Amgen's commitment has proved beneficial, and represents a significant step towards bringing this important new therapy to patients who are suffering from the debilitating effects of rheumatoid arthritis," said Aart Brouwer, Vice President, Amgen Europe.

I have seen people with debilitating fears of speaking become poised and polished.