prerenal

In our case, the sequence of events was probably development of prerenal failure due to the natriuretic effect of trimethoprim, resulting in further accumulation of trimethoprim and increasing the risk of hyperkalaemia.

Theoretically, the chances of conversion from prerenal failure to intrinsic renal failure are more in elderly patients due to the presence of comorbid conditions and age-related changes.

Patients with acute prerenal failure and volume overload manifest a particularly challenging diagnosis.

The return of the BUN and serum creatinine to normal levels following fluid therapy was consistent with prerenal failure. Rapid correction of hypernatraemia may lead to central myelinosis, and it is an alternative cause of neurological deterioration.

In special circumstances like pregnancy, prerenal failure, renal failure, and where intravenous urography cannot be used or should be avoided colour Doppler waveform studies (Ureteric Jet) and renal resistive index may prove to be valuable.

Acute gastroenteritis with viral infection is the most common cause of severe diarrhea in infants and young children, often eliciting severe dehydration and prerenal failure [1, 2].