If you’ve read the other answers then you know that you can’t read a runtime value from a compiletime macro (or rather, you can’t know the value it will have at runtime at compiletime as you can’t see the future). So let’s ask a different question: how can you bind the variables in your list known at runtime.
In the case where your list isn’t really variable and you just want to give it a single name you could use macroexpand:
(defun symbol-list-of (x env) (etypecase x (list x) (symbol (macroexpand x env)))) (defmacro let-bind (vars vals &body body &environment env) (let* ((vars (symbol-list-of vars env)) (syms (loop for () in vars collect gensym))) `(destructuring-bind ,syms ,vals (let ,(loop for sym in syms for bar in vars collect (list var sym)) ,@body))))
This would somewhat do what you want. It will symbol-macroexpand the first argument and evaluate the second.
What if you want to evaluate the first argument? Well we could try generating something that uses eval. As eval will evaluate in the null lexical environment (ie can’t refer to any external local variables), we would need to have eval generate a function to bind variables and then call another function. That is a function like (lambda (f) (let (...) (funcall f)). You would evaluate the expression to get that function and then call it with a function which does he body (but was not made by eval and so captures the enclosing scope). Note that this would mean that you could only bind dynamic variables.
What if you want to bind lexical variables? Well there is no way to go from symbol to the memory location of a variable at runtime in Common Lisp. A debugger might know how to do this. There is no way to get a list of variables in scope in a macro, although the compiler knows this. So you can’t generate a function to set a lexically bound symbol. And it would be even harder to do if you wanted to shadow the binding although you could maybe do it with some symbol-macrolet trickery if you knew every variable in scope.
But maybe there is a better way to do this for special variables and it turns out there is. It’s an obscure special form called progv. It has the same signature that you want let-bind to have except it works. link.