Questions tagged [t-test]
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4 questions
4 votes
1 answer
46 views
How can I specify pairwise comparisons of interest rather than computing all possible comparisons with something like Tukey?
Here is a subset of my df. How can I run pairwise comparisons of median expression between disease status for each clus_ft and use Bonferroni correction? For example, from this df subset, I would want ...
- 41
0 votes
1 answer
102 views
conducting a ttest on a board of 1000 genes in 50 peope divided into to groups(A and B). pvalues are different each time
I am struggling in conducting at test on a board of 1000 genes in 50 individuals divided into to groups (A and B). I have a dataset of 1000 genes of two groups of people (total individuals=50) group A ...
1 vote
0 answers
52 views
enrichment of DE genes within wide regions not pathways, hypergeometric test or GSEA?
I haven't found any relevant posts, so here is my question (it's more a question on statistics I believe): I have the deseq2 output of DE genes( around 25000 genes) , and among them 1000 are ...
- 11
1 vote
1 answer
220 views
What statistical test to apply for DE after CibersortX deconvolution?
This question was also asked on Biostars I am running CibersortX in high-resolution mode (which yields estimates of gene values per sample). After that, I want to perform DE between two conditions on ...
- 149