In working on a spectrophotometer design, I have to make a design decision for implementing the photodiode front-end amplifier and ADC. One of the requirements I have set is a dynamic range for the input of 10^5 in terms of radiant intensity, translating directly to photodiode current of, say, 10pA to 1uA, so, at least 17 bits of resolution. I have settled for the MCP3550 22-bit S/D ADC with an appropriate reference and likely an LMP7721 ultra-low Ib opamp for the TIA amplifier.
The design requires that the photodiode is positioned away from the electronics by about 0.5-1m. It will be enclosed in a full metal case with a window for the light input. The analog electronics will also reside in a shielded enclosure, uC interface will be galvanically isolated, as will be the analog power rails. Sources of interference include a large (150VA) mains transformer and a NEMA 17 stepper motor and driver, also in ~0.5m vicinity.
My question is whether it is better to convert the photocurrent to a voltage immediately at the detector and send the output voltage (e.g. 10uV to 1V) via a shielded cable, which also carries the supply voltages, to the ADC in the enclosure, or if sending the photocurrent via a triaxial cable back to the enclosure presents any advantage. I have illustrated the two designs below.
The relevant questions are as follows:
- Is it preferable to send a single ended (or pseudo-differential, as shown) uV-level voltage signal along a shielded twisted pair or to use a double-shielded coax and transmit pA-level photocurrent?
- In design 2, what is the effect of cable capacitance on input capacitance of the TIA? The inner "guard" shield appears bootstrapped, but is it in reality.
- In design 2, to gain some extra dynamic range, I have shown the ADC's "-" input tied to Vref, such that I can measure a 0-5V signal as -2.5 to +2.5V from the perspective of the ADC, but now the input is truly single-ended. However, given the close proximity of the opamp and ADC in this design, this shouldn't come at a penalty?
- In both designs, I have shown the shield as connected to a separate ground, which I plan to be protective earth (PE). Is this meaningful in a fully isolated system with high DC and AC impedance to PE? Thank you in advance,


