Here is an example from What is an ABI and why is it needed to interact with contracts?
contract Foo { function baz(uint32 x, bool y) returns (bool r) { r = x > 32 || y; } }
If we wanted to call baz() with the parameters 69 and true, we would pass 68 bytes in total, which can be broken down into:
0xcdcd77c0: the Method ID. This is derived as the first 4 bytes of the Keccak-256 hash of the ASCII form of the signature baz(uint32,bool). 0x0000000000000000000000000000000000000000000000000000000000000045: the first parameter, a uint32 value 69 padded to 32 bytes. (69 is hex 0x45.) 0x0000000000000000000000000000000000000000000000000000000000000001: the second parameter - boolean true, padded to 32 bytes
The 68 bytes is the calldata: 0xcdcd77c000000000000000000000000000000000000000000000000000000000000000450000000000000000000000000000000000000000000000000000000000000001.