Setting up OpenTelemetry needs additional manual steps when working with uWSGI as documented here: https://opentelemetry-python.readthedocs.io/en/latest/examples/fork-process-model/README.html#uwsgi-postfork-decorator

This should not be required if a user is invokes the opentelemetry-instrument command to auto-instrument their uWSGI based service.

Hint: pre instrumentation hook might be helpful to implement this.