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BUG: Error in deparse(substitute(e2, env = caller_env(2))) : 'S4SXP': should not happen - please report

bugSomething isn't workingSomething isn't working

Status: Open.

#10341 In satijalab/seurat;

· Traumaticc opened on Mar 22, 2026

BUG: RunUMAP in Seurat5 fails with Matrix error

bugSomething isn't workingSomething isn't working

Status: Open.

#10340 In satijalab/seurat;

· FerallOut opened on Mar 22, 2026

Bug/Performance: FindAllMarkers with BPCells repeatedly writes transposed matrices to tempdir(), causing storage exhaustion and basic_ios::clear errors on large datasets

bugSomething isn't workingSomething isn't working

Status: Open.

#10334 In satijalab/seurat;

· yangqi-su opened on Mar 17, 2026

BUG: As.Seurat error converting SCE when named 'object'

bugSomething isn't workingSomething isn't working

Status: Open.

#10332 In satijalab/seurat;

· Ivo-Borkus opened on Mar 16, 2026

MapQuery Error during bridge integration (cross modality): Error in Matrix::sparseMatrix(i = is, j = nn_idxv, x = xs, dims = dims) : 'dims' must contain all (i,j) pairs

Status: Open.

#10328 In satijalab/seurat;

· bapoorva opened on Mar 12, 2026

split() before Sketch Integration takes forever. Any workaround?

Status: Open.

#10316 In satijalab/seurat;

· hchintalapudi opened on Mar 3, 2026

What have residual features argument in SCTransform done?

Status: Open.

#10297 In satijalab/seurat;

· shihsama opened on Feb 5, 2026

If I need to do downsampling before DEA ?

Status: Open.

#10291 In satijalab/seurat;

· Xiangyi-Deng opened on Jan 30, 2026

BUG: <insert-descriptive-title>Seurat::merge() Error "invalid class 'dgCMatrix' object: 'i' slot is not increasing within columns" - Same Code Works on One Server but Fails on Another

bugSomething isn't workingSomething isn't working

Status: Open.

#10288 In satijalab/seurat;

· wangbenwang123 opened on Jan 28, 2026

TransferData error :Error in .subscript.2ary(x, i, , drop = TRUE) : subscript out of bounds

Status: Open.

#10279 In satijalab/seurat;

· xiangyupan opened on Jan 17, 2026

BUG: _R_CHECK_LIMIT_CORES_ was set to TRUE during initialization

bugSomething isn't workingSomething isn't working

Status: Open.

#10275 In satijalab/seurat;

· kotai-michael opened on Jan 15, 2026

Feature Request: assay option for FeaturePlot

enhancementNew feature or requestNew feature or request

Status: Open.

#10268 In satijalab/seurat;

· assaron opened on Jan 7, 2026