Questions tagged [biostatistics]
The science of statistics applied to the analysis of biological or medical data.
1,450 questions
0 votes
0 answers
29 views
Is statistical analysis possible on simple phosphatase assay? [closed]
For a uni course I have to write a report on an experiment I did that boils down to comparing enzyme activity. I'd like to be able to say one protein has a significantly higher activity than the other....
- 1
0 votes
0 answers
11 views
How to determine unit size for Taylor's Power Law?
How to determine unit size for Taylor's Power Law to assess overall degree of heterogeneity in spatial patterns? I tested eight different varieties (A, B, C, D, E, F, G, H) in the field against a ...
- 435
2 votes
1 answer
58 views
Should differential expression analysis be incorporated in cross validation for training machine learning models?
I'm conducting some experiments using TCGA-LUAD clinical and RNA-Seq count data. I'm building machine learning models for survival prediction (Random Survival Forests, Survival Support Vector Machines,...
- 21
4 votes
1 answer
81 views
Is UMAP advisable for clustering analysis in microbiome data?
I have a soil microbiome study in which we obtained two profiles (200 samples x 100,000 features and the same 200 samples x 5000 features, respectively), as well as a number of soil parameters ...
- 149
0 votes
0 answers
42 views
Unaccounted for residual dependence in hierarchical GAM
I'm in need of some advice on how to account for residual dependence in a fitted GAM that doesn't appear to be driven by temporal structure in the data. In summary, I am working with a long-term ...
2 votes
0 answers
47 views
GLMM BACI and covariates
I’m hoping to do a GLMM on this BACI study I have been doing, and wanted to see if it is normal or feasible to add in some habitat covariates that might help explain response variable, as someone ...
9 votes
4 answers
759 views
Is a normality test always performed on errors and not on raw data?
This question is mainly because I see many tutorials, whether on YouTube videos or on websites, forums, and the like, where when using software like SPSS, they always apply normality tests directly to ...
0 votes
0 answers
40 views
Which hypothesis test should I use when response variables are correlated （MRI， brain functions）?
I'm facing a multiple testing problem. I have two groups of people (health and disease), and I'm interested in the differences in their brain functions. There are many measures of brain function, and ...
