You may find this perl and elisp combination useful. It allows you to pipe data to a buffer. Subsequent invocations using the same buffer-name will append the new lines to the same buffer.
You can "edit" the buffer, but the edit in no way reflects back to the source (which is a pipe) ... It doesn't show any line numbers, though you can tweak the input to include a numbered prefix for each line.
from=50000000 to=50000010 <file_50 head -n "$to" | tail -n +"$from" | e-sink.pl
In the buffer:
<<<<< start: 2012-09-09T01:39:49 1000000 VSjU K97X5Z dFcc ZZd2OqQ PzbnphT yQBTt LOic Ks sPXrq tty oy dA8 SD BvO daZ KFPr44X X0m3BI eR4go YjFp7e vbJr3oe Y0OGgH3 uPfz yfq59 we rm L9iD ugcJBND daS 7pO lwUFzNE HPlPW fmPZ vpRs Rx EFeHaFM b0 1B ncr Db324 vwO Un34R HDZS wq9zg W013 5JGly kAfP QPpjjyh pXMAw I1 CGKDc23 qCBnP <<<<< end: 0.630s
Or, with line numbers added:
from=50000000 to=50000010 <file_50 head -n "$to" | tail -n +"$from" | nl -v$from -ba -w${#to} | e-sink.pl
In the buffer:
<<<<< start: 2012-09-09T01:53:44 50000000 1000000 50000001 VSjU K97X5Z dFcc ZZd2OqQ PzbnphT 50000002 yQBTt LOic Ks sPXrq tty oy 50000003 dA8 SD BvO daZ KFPr44X 50000004 X0m3BI eR4go YjFp7e vbJr3oe Y0OGgH3 uPfz yfq59 50000005 we rm L9iD ugcJBND daS 50000006 50000007 7pO lwUFzNE HPlPW fmPZ vpRs Rx EFeHaFM 50000008 b0 1B ncr Db324 vwO Un34R 50000009 HDZS wq9zg W013 5JGly 50000010 kAfP QPpjjyh pXMAw I1 CGKDc23 qCBnP <<<<< end: 0.768s
I found this on a StackOverflow Q/A
ed?57890000,57890010p