You can try this :
import sys from qgis.core import ( QgsApplication, QgsProcessingFeedback, QgsVectorLayer ) # See https://gis.stackexchange.com/a/155852/4972 for details about the prefix QgsApplication.setPrefixPath('/usr', True) qgs = QgsApplication([], False) qgs.initQgis() # Append the path where processing plugin can be found sys.path.append('/docs/dev/qgis/build/output/python/plugins') import processing from processing.core.Processing import Processing Processing.initialize() vlayer = QgsVectorLayer('P:/Test/qgis_test/poly_test.shp', "poly_test", "ogr") parameter_dictionary = { 'INPUT' : vlayer, 'DISTANCE' : 500, 'SEGMENTS' : 25, 'END_CAP_STYLE' : 0, 'JOIN_STYLE' : 1, 'MITER_LIMIT' : 10, 'DISSOLVE' : False, 'OUTPUT' : 'memory:' } buffer_result = processing.run("native:buffer", parameter_dictionary) output = buffer_result['OUTPUT']
Also do not forget to check the QGIS Documentation
References: