ImageValuePositions, new in 9, can return a list of white pixel positions.
i = Import@"https://i.sstatic.net/opzqB.png"; p = ImageValuePositions[i, White] // Mean (* {298.896, 21.3231} *) HighlightImage[i, {p}, Method -> {"CrossMarkers", 5}]
Update: Surrounding rectangle
Get the min/max of white pixel coordinates.
whites = ImageValuePositions[i, White]; corners = Transpose[{ Through[{Min, Max}[First /@ whites]], Through[{Min, Max}[Last /@ whites]]}] (* {{218.5, 0.5}, {373.5, 50.5}} *)
Make a rectangle boundary and highlight that region on the image.
rect = corners /. {{x1_, y1_}, {x2_, y2_}} :> With[{dx = 2}, Join[ Table[{x1, y1} + {0, y}, {y, 0, y2 - y1, dx}], Table[{x1, y2} + {x, 0}, {x, 0, x2 - x1, dx}], Table[{x2, y2} - {0, y}, {y, 0, y2 - y1, dx}], Table[{x2, y1} - {x, 0}, {x, 0, x2 - x1, dx}]]]; HighlightImage[i, rect, Method -> {"DiskMarkers", 1}]